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GnRH antagonist/agonist

时间:2019-03-29 16:52:33 阅读数:0


1. GnRH antagonist

NO

Product

CAS No

Scope of application

Key quality indicator

purity

isomer

Specific impurity

*Max1

Moisture

1

Fmoc-3-(2-naphthyl)-D-Ala-OH

138774-94-4

Most products

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤1.0%

2

Ac-3-(2-naphthyl)-D-Ala-OH

37440-01-0

Most products

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤1.0%

3

Fmoc-3-(3-pyridinyl)-D-Ala-OH

142994-45-4

Most products

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤1.0%

4

Fmoc-4-chloro-D-Phe-OH

142994-19-2

Most products

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤1.0%

5

Fmoc-D-Cit-OH

200344-33-8

Cetrorelix

≥99.5%

≤0.1%

≤0.1%

≤0.2%

≤1.0%

6

Fmoc-D-Ala-OH.H2O

79990-15-1

Most products

≥99.5%

≤0.1%

≤0.1%

≤0.2%

≤6.5%

7

Fmoc-D-Aph(tBuCbm)-OH

1433975-21-3

Degarelix

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤1.0%

8

Fmoc-D-Aph(Cbm)-OH

324017-22-3

Degarelix

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤1.0%

9

Fmoc-L-Aph(L-Hor)-OH

1253282-31-3

Degarelix

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤1.0%

10

Fmoc-L-Lys(iPr,Boc)-OH

201003-48-7

Degarelix/Abarelix/Antide

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤1.0%

11

Fmoc-N-Me-Tyr(tBu)-OH

133373-24-7

Abarelix

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤1.0%

12

Fmoc-D-Asn(Trt)-OH

180570-71-2

Abarelix

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤1.0%

13

Fmoc-HomoArg(Et)2-OH.HCl

1864003-26-8

Ganirelix

≥95.0%

≤0.5%

≤1.0%

≤2.0%

≤2.0%

14

Fmoc-D-HomoArg(Et)2-OH.HCl

2098497-24-4

Ganirelix

≥95.0%

≤0.5%

≤1.0%

≤2.0%

≤2.0%

15

Fmoc-Lys(nicotinoyl)-OH

252049-11-9

Antide

≥98.0%

≤0.2%

≤0.3%

≤0.5%

≤1.0%

16

Fmoc-D-Lys(nicotinoyl)-OH

252049-12-0

Antide

≥98.0%

≤0.2%

≤0.3%

≤0.5%

≤1.0%

  * Max1 = Max Unknown Impurity


Other Indicator:

  - Acetic Acid: ≤0.02% (All Products)

  - Ethyl Acetate: ≤0.5% (All Products)

  - Alcohol : ≤0.5% (All Products)


PL-瑞克类.png

2. GnRH agonist 

NO

Product

CAS No

Scope of application

Key quality indicator

purity

isomer

Specific impurity

*Max1

Moisture

17

Fmoc-D-Trp(Boc)-OH

163619-04-3

Triptorelin/Deslorelin/Octreotide

≥98.5%

≤0.2%

≤0.3%

≤0.5%

≤2.0%

18

Pyr-OH

98-79-3

Most products

≥99.5%

≤0.1%

≤0.1%

≤0.2%

≤1.0%

19

Fmoc-D-Ser(tBu)-OH

128107-47-1

Buserelin/Goserelin

≥99.5%

≤0.1%

≤0.1%

≤0.2%

≤1.0%

20

Fmoc-Tyr (Bzl)-OH

71989-40-7

Buserelin/Goserelin

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤1.0%

21

Fmoc-Arg (NO2)-OH

58111-94-7

Buserelin/Goserelin

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤1.0%

22

Fmoc-Ser(Trt)-OH

111061-56-4

Buserelin/Goserelin

≥99.5%

≤0.1%

≤0.1%

≤0.2%

≤1.0%

23

Fmoc-Trp-OH

35737-15-6

Buserelin/Goserelin

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤2.0%

24

Fmoc-His-OH

116611-64-4

Buserelin/Goserelin

≥99.0%

≤0.2%

≤0.3%

≤0.3%

≤2.0%

25

Fmoc-D-Leu-OH

114360-54-2

Leuprorelin

≥99.5%

≤0.1%

≤0.1%

≤0.2%

≤1.0%

26

Fmoc-2-methyl-D-Trp-OH

196808-79-4

Hexarelin/Examorelin

≥98.0%

≤0.2%

≤0.3%

≤0.5%

≤1.0%

27

Fmoc-D-Phe-OH

86123-10-6

Hexarelin

≥99.5%

≤0.1%

≤0.1%

≤0.2%

≤1.0%

28

Fmoc-D-His(Bzl)-OH

1417638-37-9

Histrelin

≥98.0%

≤0.2%

≤0.3%

≤0.5%

≤1.0%

  * Max1 = Max Unknown Impurity


Other Indicator:

  - Acetic Acid: ≤0.02% (All Products)

  - Ethyl Acetate: ≤0.5% (All Products)

  - Alcohol : ≤0.5% (All Products)

PL-瑞林类.png

Fmoc-Gly-OH·H2O 35661-39-3.jpg

Structural Representation