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GLP-1 Protected Amino Acid

时间:2019-03-29 15:46:38 阅读数:0


NO

Product

CAS   No

Scope   of application

Key   quality indicator

purity

isomer

SI *

Max *

Moisture

1

Fmoc-Lys(Mtt)-OH

167393-62-6

Lysine side chain modification

≥99.0%

≤0.1%

≤0.2%

≤0.3%

≤1.0%

2

Fmoc-Lys(Alloc)-OH

146982-27-6

Lysine side chain modification

≥99.5%

≤0.1%

≤0.1%

≤0.2%

≤1.0%

3

Fmoc-Lys(ivDde)-OH

150629-67-7

Lysine side chain modification

≥98.0%

≤0.2%

≤0.3%

≤0.5%

≤1.0%

4

Fmoc-Lys(Mmt)-OH

159857-60-0

Lysine side chain modification

≥98.0%

≤0.2%

≤0.3%

≤0.5%

≤1.0%

5

Fmoc-Glu-OtBu

84793-07-7

Liraglutide /Semaglutide

≥99.5%

≤0.1%

≤0.1%

≤0.2%

≤1.0%

6

Glu-OtBu

45120-30-7

Liraglutide /Semaglutide

≥99.5%

≤0.1%

≤0.1%

≤0.2%

≤1.0%

7

Octadecanedioic acid

871-70-5

Semaglutide

≥99.0%

/

≤0.2%

≤0.3%

≤1.0%

8

Octadecanedioic acid   mono-tert-butyl ester

843666-40-0

Semaglutide

≥99.0%

/

≤0.2%

≤0.3%

≤1.0%

9

tBu-OOC-C16-CO-Glu-OtBu

1188328-39-3

Semaglutide Fragment A

≥98.0%

≤0.2%

≤0.5%

≤0.5%

≤1.0%

10

AEEA

134978-97-5

Semaglutide/艾博卫肽

≥99.0%

/

≤0.2%

≤0.3%

≤1.0%

11

AEEA-OH.HCl

134979-01-4

Semaglutide/艾博卫肽

≥99.0%

/

≤0.2%

≤0.3%

≤1.0%

12

Fmoc-AEEA-OH

166108-71-0

Semaglutide/艾博卫肽

≥99.0%

/

≤0.2%

≤0.3%

≤1.0%

13

Boc-AEEA-OH

108466-89-3

Semaglutide

≥99.0%

/

≤0.2%

≤0.3%

≤1.0%

14

AEEA-AEEA

1143516-05-5

Semaglutide

≥98.0%

≤0.2%

≤0.5%

≤0.5%

≤1.0%

15

Fmoc-AEEA-AEEA-OH

560088-89-3

Semaglutide Fragment B

≥98.0%

≤0.2%

≤0.5%

≤0.5%

≤1.0%

16

Octa(OtBu)-Glu(ɑ-OtBu)-AEEA-AEEA-OH

1118767-16-0

Semaglutide Fragment C

≥98.0%

≤0.2%

≤0.5%

≤0.5%

≤1.0%

17

tBu-OOC-C16-CO-Glu(AEEA-AEEA-NHS)-OtBu

1118767-15-9

Semaglutide Fragment D

≥96.0%

≤0.5%

≤1.0%

≤1.0%

≤1.0%

18

Fmoc-Lys(tBu-OOC-C16-CO-Glu(AEEA-AEEA)-OtBu)-OH

1662688-20-1

Semaglutide Fragment E

≥96.0%

≤0.5%

≤1.0%

≤1.0%

≤1.0%

19

Boc-His(Trt)-OH

32926-43-5

The end is histidine

≥99.5%

≤0.1%

≤0.1%

≤0.2%

≤4.0%

20

Fmoc-Aib-OH

94744-50-0

Semaglutide

≥99.5%

/

≤0.1%

≤0.2%

≤1.0%

21

Boc-His(Trt)-Aib-OH

2061897-68-3

Semaglutide

≥99.0%

≤0.1%

≤0.2%

≤0.3%

≤2.0%

22

Fmoc-Glu(OtBu)-Gly-OH

866044-63-5

GLP-1 analogue

≥99.5%

≤0.1%

≤0.2%

≤0.2%

≤1.0%

23

Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH

1169630-31-2?

Semaglutide Fragment F

≥98.0%

≤0.2%

≤0.5%

≤0.5%

≤1.0%

24

Boc-His(Trt)-Aib-Glu(OtBu)-Gly-NHS

1169630-40-3

Semaglutide Fragment G

≥96.0%

≤0.5%

≤1.0%

≤1.0%

≤1.0%

25

Fmoc-Arg(pbf)-Gly-OH

660846-80-0

GLP-1 analogue

≥99.5%

≤0.1%

≤0.2%

≤0.2%

≤1.0%

26

Fmoc-Ala-Ala-OH

87512-31-0

GLP-1 analogue

≥99.5%

≤0.1%

≤0.2%

≤0.2%

≤1.0%

27

Fmoc-Thr(tBu)-Phe-OH

1260609-75-3 ?

GLP-1 analogue

≥99.5%

≤0.1%

≤0.2%

≤0.2%

≤1.0%

28

Palmitic acid

57-10-3

Liraglutide Fragment 1

≥99.0%

/

≤0.2%

≤0.3%

≤1.0%

29

Palm-Glu-OtBu

NA

Liraglutide Fragment 2

≥98.0%

≤0.2%

≤0.5%

≤0.5%

≤1.0%

30

Palm-Glu(NES)-OtBu

NA

Liraglutide Fragment 3

≥96.0%

≤0.5%

≤1.0%

≤1.0%

≤1.0%

31

Fmoc-Lys(Palm-Glu-OtBu)-OH

1491158-62-3

Liraglutide

≥98.0%

≤0.2%

≤0.5%

≤0.5%

≤1.0%

32

Hexadecanedioic acid

505-54-4

Insulin degludec

≥99.0%

/

≤0.2%

≤0.3%

≤1.0%

33

Hexadecanedioic acid   mono-tert-butyl ester

843666-27-3

Insulin degludec

≥99.0%

/

≤0.2%

≤0.3%

≤1.0%

34

tBu-OOC-C14-CO-Glu-OtBu

NA

Insulin degludec Fragment I

≥98.0%

≤0.2%

≤0.5%

≤0.5%

≤1.0%

35

tBu-OOC-C14-CO-Glu(NES)-OtBu

NA

Insulin degludec Fragment II

≥96.0%

≤0.5%

≤1.0%

≤1.0%

≤1.0%

 

       SI *= Specific Impurity

       Max*= Max Unknown Impurity


Other Indicator:

  - Acetic Acid: ≤0.02% (All Products)

  - Ethyl Acetate: ≤0.5% (All Products)

  - Alcohol : ≤0.5% (All Products)



Fmoc-Gly-OH·H2O 35661-39-3.jpg

Structural Representation of Fmoc-Gly-OH


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