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Syn-Ake

时间:2019-03-04 09:46:28 阅读数:0


类蛇毒肽.png


Structural Representation of Syn-Ake

Chemical Properties

Product Name

SYN-AKE / Dipeptide Diaminobutyroyl Benzylamide

Chinese Name

二肽二氨基丁酰苄基酰胺(类蛇毒肽)

CAS NO

823202-99-9

MF

C19H29N5O3(C2H4O2)2

Sequence

beta-Ala-Pro-Dab-NHBzl

Molecular Weight

495.569

Package

1g, 10g,   100g,500g

Appearance: White Freeze-dried Powder

Storage; 2 ~8 ℃

Application

Cosmetic raw materials

 


Advantage of Readline

- Purity(HPLC):99%Content: 75%

- Acetic Acid:15%Moisture:  8%

- 20% below market price

- 10kg per month


Efficacy and Mechanism of Action

Tripeptide-3 (sequence: beta-Ala-Pro-Dab-NHBn-2-Acetate), also known as dipeptide diaminobutyryl benzylamide diacetate or SYN®-AKE, mimics the action of waglerin-1, a peptide found in venom. V snake Tropidolaemus wagleri. Tripeptide-3 acts on the postsynaptic membrane and is a reversible antagonist of acetylcholine receptor.


Experimental data and research reports

Tripeptide-3 has been tested in different preparations used locally in animal models, ranging in concentration from 1% to 4%. Shortly after the application of the preparation, the results were claimed to smoothly simulate the appearance of wrinkles and expression lines. The results showed that when 4% local solution was used, TP3 could reduce wrinkles by 52% after 28 days. A three-month study (37 female volunteers) showed that tripeptide-3 treatment provided immediate and long-term improvements in fine and coarse wrinkles.